. These are organic compounds containing an octyl chain attached to the sulfur of a sulfonic acid (or a derivative thereof), where all hydrogens of the octyl chain are replaced by fluorine atoms. These results supported the notion that autophagic cell death contributed to PFOS-induced hepatotoxicity. Ableitung von HBM-I-Werten für Perfluoroktansäure (PFOA) und Perfluoroktansulfonsäure (PFOS) - Stellungnahme der Kommission Humanbiomonitoring des Umweltbundesamts PFOS can be synthesized in industrial production or result from the degradation of precursors. EPA/815-S-17-00. The following discusses telomer environmental toxicity.In addition to the assessment of both acute and chronic toxicity in aquatic organisms, studies have been conducted evaluating the effects of PFOS on the endocrine system with regard to steroidogenesis, endocrine related gene expression, effects on the pituitary-hypothalamic-thyroidal axis and reproductive endpoints.
The perfluorinated compounds are used as precursor materials in the synthesis of very high molecular weight fluorinated polymers. Autophagy stimulator rapamycin further decreased cell viability and increased LDH release. Many volatile PFC precursors, such as perfluorooctane acid ester, perfluorooctane amide, and perfluorooctane alkanolamide, can be transported over long distances and then degraded into PFCs (such as PFOS) that do not easily volatilize. Listen to the audio pronunciation in several English accents. Fourth largest river basin in Central Europe PFOS and PFOA induce reproductive and developmental toxic effects in different species and organs.
A major primary producer in semi-natural and anthropogenic affected ecosystems. Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are fluorinated hydrocarbons used as water-, oil-, and stain-resistant coatings in fabrics, leather, and carpets, and oil-resistant coatings for paper products for food contact, and also as photographic emulsifier, aviation … Region in the chemical triangle of Central Germany Fine insoluble mineral or organic particles in the water phase C'est un perturbateur endocrinien et un polluant inscrit à l'Annexe B de la Convention de Stockholm sur les polluants organiques persistants. By continuing you agree to the Copyright © 2020 Elsevier B.V. or its licensors or contributors. The roe deer is the most common of the larger herbivores (first order-consumer) to be found in the wild in Europe. 3M began to phase it out in 2000, but it and similar perfluorinated compounds continue to be produced in China.Because of the multiple hazards imposed by PFOS and its cousins (see hazard information box), efforts have been made to Learn how ACS can help you stay ahead in the world of chemistry.1155 Sixteenth Street, NW, Washington, DC 20036, USA | For your security, this online session is about to end due to inactivity.If you do not respond, everything you entered on this page will be lost and you will have to login again. These materials are not natural products and are purely anthropogenic in origin. It was confirmed by elevated LC3-II levels in Western blot analysis. クタンスルホン酸（PerFluoroOctaneSulfonic acid） の略称で、有機フッ素化合物の一種です。 PFOS は1940 年代にアメリカで開発された界面 活性剤で、耐熱性、耐薬品性など非常に優れた安 定性を持ち、表面張力を大きく低下させる Perfluorooctanesulfonic acid is an anthropogenic fluorosurfactant and global pollutant. National Park in the largest brackish water (Bodden) habitat of the world. Data Summary, 2017. PFOS was the key ingredient in Scotchgard, a fabric protector made by 3M, and numerous stain repellents. 化学物質「ペルフルオロオクタンスルホン酸」の詳細情報です。J-GLOBAL 科学技術総合リンクセンターは研究者、文献、特許などの情報をつなぐことで、異分野の知や意外な発見などを支援する新しいサービスです。またJST内外の良質なコンテンツへ案内いたします。 This production method, whilst cleaner and resulting in a much more pure product than ECF, is not known to have been widely used except for the production of reagent grade PFOS and analytical standards. PFOS was the key ingredient in Scotchgard™ surface protection products produced by 3M. Perfluorooctanesulfonic acid, usually abbreviated to PFOS, was once a widely used surfactant in fabric protectors, firefighting foams, and photolithographic chemical mixtures. I’m a bad actor that makes excellent foams.
The Upper Bavarian Tertiary Uplands are a part of the Southern German Molasse Basin Perfluorooctanesulfonic acid (PFOS) is a fluorosurfactant with a nonpolar fully fluorinated C-chain and a polar sulfonic group.
Perfluorooctanesulfonic acid (PFOS) is a fluorosurfactant with a nonpolar fully fluorinated C-chain and a polar sulfonic group. It was introduced in 1949 by 3M Co. (then known as Minnesota Mining and Manufacturing Co.).By 1968, traces of PFOS began to appear in human blood. Soil is livelihood and biosphere for humans, animals, plants and soil organisms.
They are not reactive and are not easily degraded, making them persistent and present in the environment and in humans, where they can be transferred from the mother to the offspring during gestation and lactation. However, many chemical intermediates such as polyfluorinated iodine alkanes, sulfonyl fluorides, etc., are used in the production of fluoropolymers containing fluorotelomer or fluoroalkyl sulfonate moieties. plant litter). Additionally, in exposures to zebrafish, altered sex ratios, induced male gonadal development impairment and in FFor PFOA, the majority of the aquatic ecotoxicity studies have been conducted with the ammonium salt (APFO) of the prefluorooctanoic acid. ic acid Here are all the possible pronunciations of the word perfluorooctanesulfonic acid. Perfluorooctanesulfonic Acid Perfluorooctanesulfonic acid (PFOS) is a fluorosurfactant used most notably as the key ingredient in the fabric protector Scotchgard. plant litter). Knowledge about the exposure situation in fetuses, newborns and toddlers, since transfer of xenobiotics occur from the mother to the fetus through the umbilical cord, via mother’s milk to the newborn and via direct inhalation and ingestion to the newborn and toddler is therefore important in order to predict toxic effects.
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